Hirofumi Yamashita Selected Research

Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)

1/2019	TDP-43 levels are higher in platelets from patients with sporadic amyotrophic lateral sclerosis than in healthy controls.
7/2018	Amyotrophic Lateral Sclerosis after Receiving the Human Papilloma Virus Vaccine: A Case Report of a 15-year-old Girl.
1/2018	Overexpressed wild-type superoxide dismutase 1 exhibits amyotrophic lateral sclerosis-related misfolded conformation in induced pluripotent stem cell-derived spinal motor neurons.
12/2014	Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant.
1/2011	Colocalization of 14-3-3 proteins with SOD1 in Lewy body-like hyaline inclusions in familial amyotrophic lateral sclerosis cases and the animal model.
3/2008	Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis.
10/2007	[ALS and microglia--a player for non-cell-autonomous neuron death].
9/2007	Heat-shock protein 105 interacts with and suppresses aggregation of mutant Cu/Zn superoxide dismutase: clues to a possible strategy for treating ALS.
7/2004	Effects of mitochondrial dysfunction on glutamate receptor-mediated neurotoxicity in cultured rat spinal motor neurons.
2/2003	Phosphodiesterase inhibitors are neuroprotective to cultured spinal motor neurons.

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Hirofumi Yamashita Research Topics

Disease

10	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2019 - 02/2003
2	Fish Diseases (Fish Disease) 01/2021 - 08/2020
2	Necrosis 08/2020 - 10/2014
2	Disease Progression 12/2018 - 10/2007
1	Parkinson Disease (Parkinson's Disease) 01/2022
1	Myotonia Congenita (Thomsen Disease) 01/2022
1	Pain (Aches) 09/2021
1	VLCAD deficiency 11/2020
1	Inborn Genetic Diseases (Disease, Hereditary) 11/2020
1	Leukoencephalopathies 01/2020
1	MYD88 Deficiency 12/2018
1	Muscle Weakness 07/2018
1	Respiratory Insufficiency (Respiratory Failure) 07/2018
1	Inclusion Body Myopathy With Early-Onset Paget Disease And Frontotemporal Dementia 12/2014
1	Infections 10/2014
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 04/2014
1	Type V Distal Hereditary Motor Neuronopathy 01/2014
1	Type 2D Charcot-Marie-Tooth disease 01/2014
1	Virus Diseases (Viral Diseases) 04/2011
1	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2008
1	Motor Neuron Disease (Primary Lateral Sclerosis) 10/2007
1	Alzheimer Disease (Alzheimer's Disease) 12/2004
1	Mitochondrial Diseases (Mitochondrial Disease) 07/2004
1	Dermatitis 10/2003

Drug/Important Bio-Agent (IBA)

3	VaccinesIBA 01/2021 - 07/2018
3	Superoxide Dismutase-1IBA 01/2018 - 10/2007
2	InterferonsIBA 12/2018 - 04/2011
2	Superoxide DismutaseIBA 03/2008 - 09/2007
1	istradefyllineIBA 01/2022
1	Dopamine Agents (Dopaminergic Agents)IBA 01/2022
1	Carbamazepine (Tegretol)FDA LinkGeneric 01/2022
1	4- propionyloxy- 4- phenyl- N- methylpiperidineIBA 09/2021
1	Fatty Acids (Saturated Fatty Acids)IBA 11/2020
1	Long-Chain Acyl-CoA Dehydrogenase (Long-Chain-Acyl-Coenzyme A Dehydrogenase)IBA 11/2020
1	Macrophage Colony-Stimulating FactorIBA 01/2020
1	Proteins (Proteins, Gene)FDA Link 01/2019
1	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2019
1	Toll-Like Receptors (Toll-Like Receptor)IBA 12/2018
1	Myeloid Differentiation Factor 88IBA 12/2018
1	Papillomavirus Vaccines (HPV Vaccines)IBA 07/2018
1	Valosin Containing ProteinIBA 12/2014
1	Poly I-CIBA 10/2014
1	Carboplatin (JM8)FDA LinkGeneric 04/2014
1	Paclitaxel (Taxol)FDA LinkGeneric 04/2014
1	nobiletinIBA 04/2014
1	Glycine-tRNA LigaseIBA 01/2014
1	14-3-3 Proteins (14-3-3 Protein)IBA 01/2011
1	Cre recombinaseIBA 10/2007
1	ZincIBA 09/2007
1	CopperIBA 09/2007
1	Galantamine (Galanthamine)FDA LinkGeneric 12/2004
1	AlkaloidsIBA 12/2004
1	Glutamate Receptors (Glutamate Receptor)IBA 07/2004
1	malonic acid (malonate)IBA 07/2004
1	Antimycin AIBA 07/2004
1	Ionotropic Glutamate ReceptorsIBA 07/2004
1	Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)IBA 07/2004
1	Glutamic Acid (Glutamate)FDA Link 07/2004
1	RotenoneIBA 07/2004
1	Immunoglobulin E (IgE)IBA 10/2003
1	Phosphodiesterase 5 InhibitorsIBA 02/2003

Therapy/Procedure

1	Mastectomy (Mammectomy) 09/2021
1	Immunotherapy 07/2018
1	Drug Therapy (Chemotherapy) 04/2014